The use of Single-Use Systems (SUS) in biopharmaceutical manufacturing has changed dramatically over the years. While we have seen a steady increase in the acceptance of SUS over the past few decades, COVID has created an environment that has accelerated the shift away from fixed stainless steel bioprocesses.
Unlike other active molecules, antitumour drugs have cytotoxicity issues and therefore need to be safely encapsulated and able to reach their target sites, all of which is made possible by the use of nanoparticles. In addition, nanoparticles have unique features such as loading of insoluble antineoplastic drugs, protection of the active fraction from harsh in vivo environments, sustained release, alteration of their biodistribution, targeting to specific cells/tissues and prolonged circulation time.
In the preparation process of nanomedicine, the use of microfluidization homogenizer can significantly improve the stability and safety of drugs. By adjusting the parameters such as homogeneous pressure and flow rate, can successfully prepare nanomedicines with uniform particle size distribution. these nanomedicines have not only good effect, but also high safety. This technology has broad application prospects in the field of medicine, especially in the need to improve the oral bioavailability of scenarios, such as to improve the oral bioavailability of omeprazole.
Resveratrol (RES), a non-flavonoid polyphenolic compound present in plants, is widely used in cosmetics for its obvious antiplatelet aggregation, antibacterial, anti-aging and hypolipidemic effects.
Preparative liquid chromatograph can be used for purification of simple post-treatment products after the end of experiments in chemical, biological, pharmaceutical, and other fields, and qualitative and quantitative analysis to a certain extent. For the pharmaceutical and biological industries that require a large number of screening, it can greatly improve work efficiency.
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