YC-LPLC Production Chromatography System

YC-LPLC series is an automated low pressure, 0-6 bar, liquid chromatography (LPLC) system, designed according to cGMP and ASME BPE regulatory requirements, for biopharmaceutical manufacturing from pilot scale to production scale. The platform is designed based on PLC, easy operating with flexible design options to meet wide range of configuration and process demands.

YC-LPLC Production Chromatography System-955
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Technial Features

lThe key components of the system are imported first-line brands with reliable performance

lComply with cGMP requirements, according to ASME BPE standard manufacturing

lPart of the liquid material meets the requirements of FDA and USP Class Vi

lMeet audit trail requirements, back to all original production records

lThe software is mature， the system runs stably and reliably


  • Technical Details
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Model

LPLC 30

LPLC 60

LPLC 100

LPLC 150

LPLC 600

LPLC 1200

LPLC 2500

LPLC 4400

Pump

Four head diaphragm pump

Flow range

1.5-30L/h

3-60L/h

6-100L/h

8-180L/h

30-600L/h

50-1200L/h

100-2500L/h

300-5000L/h

Inlet / Outlet valve

2-8 inlet for Iso Skid, 4-16 for Grandient Skids, 2-8 Outlet

Pressure sensor

2-3 LABOM pressure sensors, measuring range 0-10bar, accuracy ±0.1bar

Air sensor

Two SONOTEC air sensor, at inlet and pre-column. Optional AQ sensor, adjustable.

UV

OPTEK monitor, fixed wavelength (280nm and 254nm), range 0-3AU, mercury lamp, recommended running hours: 8000 hours.

ECOM four-wavelength (200-400nm), range 0-5AU, deuterium lamp, recommended running hours: 2000 hours.

pH

The measuring range is 2-12, the accuracy is±0.1, the display accuracy is±0.01

Cond

Hamilton, detection range: 1μs-300ms/cm, measurement accuracy:±3% (1μs-100ms/cm), ±5% (100-300ms/cm)

OPTEK, detection range: 1μs-850ms/cm, measurement accuracy:±2%

Pipe material

ASME BPE (316LSS), Ra≤0.4μm

System pressure

6 bar

Air trap volume

100mL

100mL

300mL

500mL

1000mL

2500mL

3500mL

5000mL

Pipe diameter

1/4”TC

3/8”TC

1/2”TC

3/4”TC

1”TC

1.5”TC

Power supply

220VAC 50H

380VAC 50Hz

Power

1KW

2KW

3KW

5KW

Weight

100kg

120kg

200kg

300kg

600kg

800kg

Size (cm)

135H*70W*130D

132H*70W*130D

133H*70W*142D

140H*70W*158D

180H*150W*180D



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User’s Manual

    YC-LPLC Production Chromatography System
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