The SCG-Phf system is designed to meet the pilot-scale and small-scale production need.
Applications
●Monoclonal antibody
●Recombinat protein
●Vaccines
●Biochemical drug
●Antibiotics
●Natural products
●Polysaccharides
Performance
Dynamic mixer: 15ml mixing chamber
Variety of UV detector module options. External fiber optic flow cell.
Conductivity detector: 0-999.99mS/cm, temperature compensation possible.
Technical Features
• The system has various configurations to support all you need while the performance is stable to your expectations.
• Powerful SCG operating software offer intuitive and flexible method editor, system controller and data analysis tool. The same familiar user interface as the laboratory development environment for the scale up. Please note that the software is free for upgrade during the product lifetime.
• Can work with various brand chromatography column from domestic or international vendors.
• Can fit in regular chromatography refrigerator.
• SCG-Phf can satisfy gram level or even to kg level production needs.
Model | SCG-Phf |
System pump | Peek material/stainless steel, double pump with four pump heads, good biocompatibility. |
Flow rate range | Double pump gradient operation: 0.1-999.9 ml/min, double pump superimposed operation: 0.1-1999.9 ml/min |
System pressure rate | 0-2 MPa(20bar, 290psi) |
Mixer | 15 ml |
Flow rate accuracy | ±2% |
Flow rate precision | RSD<0.5% |
Supported elution | Isocratic/ramp/step gradient, in-process modification available |
UV detector | Option1)Default 280 nm imported detector, wavelengths customizable when ordering, including 2.0mm external circulation pool |
Option2)Default 260 & 280 nm imported detector, detecting both channels simultaneously, including 2.0mm external circulation pool | |
Option3)200 - 400 nm imported detector, detecting both channels simultaneously, including 2.0mm external flow cell | |
Option4)200 - 600 nm imported detector, detecting four channels simultaneously, including 2.0mm external circulation pool | |
Option5)190 - 840 nm imported detector, detecting four channels simultaneously, including 2.0mm external circulation pool | |
UV flow cell | Standard 2 mm, optional 5 mm/10 mm light range |
Wavelength precision/repeatability | ±1nm / ±0.5nm |
UV noise / drift | 0.16 mAu(1s)/ 1 mAu/h |
Conductivity sensor | 0.001-999.99 mS/cm, precision ±0.1 mS/cm or ±2% |
Temperature sensor | 0-100℃, precision±1℃, can compensate conductivity/pH result automatically |
pH sensor | 0 - 14, precision ±0.1 (2-12) |
Bubble trap | Help remove in-line bubble |
Refractive index detector | Flow rate range: 1-50 ml/min, flow cell volume: 8 μL, assay range: 2.5- 5120 μRIU |
Inlet selection valve | Option1)Provides 2 inlet buffer choices for each pump Option2)Provides 6 inlet buffer choices for each pump |
Column position valve | Supports Column Forward, Column Backward, Column + Airtrap, Bypass, and Waste |
Pre/post column pressure monitoring module | Monitor the pressure before/after the column, calculate the pressure difference, and protect the column |
Collection valve | Option1)One waste position and one sample collection outlet |
Option2)One waste position and five sample collection outlet | |
SCG Chromatography Workstation | Chromatography Workstation Software:in-house designed operation software |
Sample contact material list | PEEK, Stainless Steel, PPS, PTFE |
AC input/ power rating | 220VAC/400W |
Instrument weight (gross weight) | 87kg |
Dimension (W*H*D) | 590mm*730mm*530mm |
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