SCG-Phf Chromatography system

The SCG-Phf system is designed to meet the pilot-scale and small-scale production need.

Applications   

●Monoclonal antibody

●Recombinat protein

●Vaccines

●Biochemical drug

●Antibiotics

●Natural products

●Polysaccharides

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Performance

Dynamic mixer: 15ml mixing chamber

Variety of UV detector module options. External fiber optic flow cell.

Conductivity detector: 0-999.99mS/cm, temperature compensation possible.


Technical Features

• The system has various configurations to support all you need while the performance is stable to your expectations. 

• Powerful SCG operating software offer intuitive and flexible method editor, system controller and data analysis tool. The same familiar user interface as the laboratory development environment for the scale up. Please note that the software is free for upgrade during the product lifetime. 

• Can work with various brand chromatography column from domestic or international vendors. 

• Can fit in regular chromatography refrigerator. 

• SCG-Phf can satisfy gram level or even to kg level production needs.

SCG-Phf


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Model

SCG-Phf

System pump

Peek material/stainless steel, double pump with four pump heads, good biocompatibility.

Flow rate range

Double pump gradient operation: 0.1-999.9 ml/min, double pump superimposed operation: 0.1-1999.9 ml/min

System pressure rate

0-2 MPa(20bar, 290psi)

Mixer

15 ml

Flow rate accuracy

±2%

Flow rate precision

RSD<0.5%

Supported elution

Isocratic/ramp/step gradient, in-process modification available

UV detector

Option1)Default 280 nm imported detector, wavelengths customizable when ordering, including 2.0mm external circulation pool

Option2)Default 260 & 280 nm imported detector, detecting both channels simultaneously, including 2.0mm external circulation pool

Option3)200 - 400 nm imported detector, detecting both channels simultaneously, including 2.0mm external flow cell

Option4)200 - 600 nm imported detector, detecting four channels simultaneously, including 2.0mm external circulation pool

Option5)190 - 840 nm imported detector, detecting four channels simultaneously, including 2.0mm external circulation pool

UV flow cell

Standard 2 mm, optional 5 mm/10 mm light range

Wavelength precision/repeatability

±1nm / ±0.5nm

UV noise / drift

0.16 mAu(1s)/ 1 mAu/h

Conductivity sensor

0.001-999.99 mS/cm, precision ±0.1 mS/cm or ±2%

Temperature sensor

0-100℃, precision±1℃, can compensate conductivity/pH result automatically

pH sensor

0 - 14, precision ±0.1 (2-12)

Bubble trap

Help remove in-line bubble

Refractive index detector

Flow rate range: 1-50 ml/min, flow cell volume: 8 μL, assay range: 2.5- 5120 μRIU

Inlet selection valve

Option1)Provides 2 inlet buffer choices for each pump

Option2)Provides 6 inlet buffer choices for each pump

Column position valve

Supports Column Forward, Column Backward, Column + Airtrap, Bypass, and Waste

Pre/post column pressure monitoring module

Monitor the pressure before/after the column, calculate the pressure difference, and protect the column

Collection valve

Option1)One waste position and one sample collection outlet

Option2)One waste position and five sample collection outlet

SCG Chromatography Workstation

Chromatography Workstation Software:in-house designed operation software

Sample contact material list

PEEK, Stainless Steel, PPS, PTFE

AC input/ power rating

220VAC/400W

Instrument weight (gross weight)

87kg

Dimension (W*H*D)

590mm*730mm*530mm


Brochure

User’s Manual

    SCG-Phf Chromatography system
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